Some Publications from the past few years
Lemons, D., Fritzenwanker, J.H., Gerhart J., Lowe, C.J., McGinnis, W. (2010) Co-option of an anteroposterior head axis gene network for proximodistal patterning of appendages in early bilaterian evolution. Developmental Biology, 344, 358-362. PMCID: PMC2909331 Lemons-McGinnis-2010.pdf
Arvey, A., Hermann, A., Hsia, C.C., Ie, E., Freund., Y,, and McGinnis, W. (2010) Minimizing off-target signals in RNA fluorescent in situ hybridization, Nucleic Acids Research 38, e115, 1-7. PMCID: PMC2879521 Arvey-McGinnis-2010.pdf
Hsia, C. and McGinnis, W. (2010) Silencing of an abdominal Hox gene during embryonic development is correlated with limb development in posterior regions of a crustacean trunk. Evolution & Development, 12, 131-143. PMCID: PMC2893884 Hsia-McGinnis-2010.pdf
Paré, A., Lemons, D., Kosman, D., Beaver, W., Freund, Y., and McGinnis, W. (2009) Counting Hox transcripts within single cells in Drosophila embryos: evidence for transcriptional bursting. Current Biology 19, 2037-2042. PMCID: PMC2805773 Paré-McGinnis-2009.pdf
Pearson, J.C., Juarez, M.T., Kim, M., McGinnis, W. (2009) Multiple Transcription Factor Codes Activate Epidermal Wound Response Genes in Drosophila. Proc. Natl. Acad. Sci. USA 106, 2224-2229. PMCID: PMC2630199 Pearson-McGinnis-2009.pdf
Taghli-Lammalem, O., Hsia, C., Ronshaugen, M., and McGinnis, W. (2008) Context-dependent regulation of Hox protein function by CK2 phosphorylation sites. Development, Genes and Evolution 218, 321-332. PMCID: PMC2443945 Taghli-McGinnis-2008.pdf
N. King, 30 co-authors, D. Lemons, W. McGinnis, H Shapiro, R. Tjian, D. Rokhsar (2008) The genome of the choanoflagellate Monosiga brevicollis and the origins of metazoans. Nature 451, 783-788. PMCID: PMC2562698 King-etal-choano-genome.pdf
Beaver, W., Kosman, D., Tedeschi, G., Bier, E., McGinnis, W. and Freund, Y. (2007) Segmentation of nuclei in confocal image stacks using performance based thresholding. Conf. Proceedings, 4th IEEE International Symposium on Biomedical Imaging. pp. 53-56. http://www.biomedicalimaging.org/2007/Papers/PublicSessionIndex3.asp?Sessionid=1033
Lemons, D. and McGinnis W. (2006) Genomic evolution of Hox gene clusters, Science 313, 1918-1922. Lemons-McGinnis-2006.pdf
Tour, E., Hittinger, C.T. and McGinnis, W. (2005) Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax. Development 132: 5271-5281. Tour_McGinnis.pdf
Pearson, J.C., Lemons, D., and McGinnis, W. (2005) Modulating Hox gene functions during animal body patterning. Nature Reviews Genetics 6: 893-904. Pearson-McGinnis.pdf
Mace, K.A., Pearson, J.C., and McGinnis, W. (2005) An epidermal barrier wound repair pathway in Drosophila is mediated by grainy head. Science 308: 381-385. Epidermal barrier wound repair.pdf
Kosman, D., Mizutani, C.M., Lemons, D., Cox, W.G., McGinnis, W. and Bier, E. (2004) Multiplex detection of RNA expression in Drosophila Embryos. Science 305: 846. Multiplex detection of mRNA and miRNA.pdf
Hsia, C. and McGinnis, W. (2003) Evolution of transcription factor function. Current Opinion in Genetics and Development 13: 199-206 Transcription factor evolution and morphology.pdf
Bier, E. and McGinnis, W. (2003) Model organisms in development and disease. In Molecular Basis of Inborn Errors of Development. Eds. C.J. Epstein, R.P. Erikson, A. Wynshaw-Boris. pp. 25-45, Oxford University Press. Model organism review.pdf
Lohmann, I., McGinnis, N., Bodmer, M. and McGinnis, W. (2002) The Drosophila Hox protein Deformed sculpts head morphology by direct regulation of the apoptosis activator reaper. Cell 110: 457-466. Dfd/reaper.pdf
Ronshaugen, M., McGinnis, N., Chou, D., Zhao, J., Inglis, D. and McGinnis, W. (2002) Structure and expression patterns of Drosophila TULP and TUSP, members of the the tubby-like gene family. Mechanisms of Development 117: 209-215. DrosTulp.pdf
Ronshaugen, M., McGinnis, N. and McGinnis, W. (2002) Hox protein mutation and macroevolution of the insect body plan. Nature 415: 914-917. Hoxmacroevo.pdf
Veraksa, A, Del Campo, M. and McGinnis, W. (2000) Developmental patterning genes and their conserved functions: From model organism to humans. Molec. Gen. & Metabolism 69: 85-100. Online paper
Veraksa, A., McGinnis, N., Li, X., Mohler, J. and McGinnis, W. (2000) Cap 'n' Collar B cooperates with a small Maf subunit to specify pharyngeal development and suppress Deformed homeotic function in the Drosophila head. Dev 127, 4023-4037. Online paper