Cellular and molecular mechanisms of synapse formation, nicoinic signaling, and neural network construction.
Genetics of neuronal and epidermal morphogenesis in C. elegans.
Mechanisms of synaptic specificity during development of the central nervous system and how hormones affect neuronal activity to modify behavior
Molecular neurobiology; mechanisms of cortical development and plasticity; calcium regulation of gene expression.
The Halpain Laboratory works at the interface of c ell biology and neuroscience to investigate molecular mechanisms in the mo rphogenesis of axons, dendrites, and synapses. Through time-lapse imaging and quantitative fluorescence-based analyses, we study how the actin and microtubule cytoskeletons regulate neuronal form and function.
Huberman, Andrew Assistant Professor/Neurosciences
Genetic analysis of neural circuits.
Molecular genetic mechanisms of synapse formation, neuron circuit regulation and nerve regeneration.
Two-photon imaging of microcircuit modulations by behavior and learning in awake mice.
Neurobiology; neuronal basis of behavior; development of simple nervous systems.
Neural circuits for spatial computations and memory
Synapses in brain function and dysfunction.
Molecular neurobiology; molecular basis of electrical excitability and signal transduction in neural membranes; molecular design of channel proteins.
Neurobiology; the ubiquitin-proteasome system (UPS), one of the major cellular pathways controlling protein turnover in mammalian cells.
Visual behavior, visual neuroscience, and computational theory.
Understanding the circuits controlling the spatial and temporal structure of cortical activity.
Neurobiology; computational models of the nervous system; mechanisms for synaptic plasticity.
Developmental neurobiology; control of expression of neuronal phenotypes
Systems neurobiology; representation and processing of olfactory information in simple olfactory system.
Molecular and cellular mechanisms of axon pathfinding, target specificaton and neuronal migration in nervous system development