Alexander Weidemann received his MD form the Humboldt University in Berlin in 2000. He did his doctoral thesis on promoter regulation in the lab of Prof. V. Regitz-Zagrosek at the German Heart Center Berlin. From 2001 to 2004 he worked as a resident in the Department of Nephrology and Medical Intensive Care at the University Hospital Charite, Berlin. From 2004 he continued his medical training and worked as a postdoc in the lab of Prof. K.-U. Eckardt at the Department of Nephology and Hypertension, University of Erlangen-Nurmenberg. He joined Randy Johnson’s lab in October 2006.

My current interest is the hypoxic response in astrocytes and how it can affect the systemic physiology. These cells have important supportive function in the brain and for the blood-brain barrier. Using genetic models with conditional knockouts of several genes (e.g. VHL, HIF-isoforms and VEGF) involved in the hypoxic response,  I try to understand basic regulatory pathways of the HIF-response and try to assess phenotypical changes beyond neuronal cells which occur when the system is manipulated in vivo in astrocytes.

Christian Stockmann received his MD from the University of Duisburg-Essen in 2005. He did his doctoral thesis on oxygen-dependent gene expression in monocytes/macrophages in the lab of Prof. J. Fandrey at the Department of Physiology, University of Duisburg-Essen. From 2005 on he worked as a postdoc Prof. J. Fandrey's lab before he joined Randy Johnson’s lab in March 2006.

My current research is focused on monocytes/macrophages. These cells are part of the innate immune system and play an important role in many diseases. Using genetic models with a conditional knockout of Vascular Endothelial Growth Factor (VEGF), I am investigating the effect of macrophage-derived VEGF on several physiological (e.g. wound healing) as well pathological processes (e.g. initiation and progression of breast cancer, development of pulmonary fibrosis).

Jay Kim's information can be found on his website.

http://openwetware.org/wiki/User:Jungwhan_Kim

Norihiko Takeda received his MD from the Department of Medicine, University of Tokyo in 1996. From 1996 to 1998, he worked as a resident of Internal Medicine. From 1998 to 2000 he worked as a clinical fellow of Cardiology in Sakakibara Heart Institute. From 2001 to 2005 he did his doctoral thesis in the laboratory of Professor Nagai at the department of cardiovascular medicine, Graduate School of Medicine, University of Tokyo. He continued his study in the lab, and also worked as an instructor in the department of Cardiovascular Medicine, University of Tokyo from 2006. He joined Randy Johnson’s lab as a postdoc in January 2008.

My current interest is the crosstalk between hypoxia and inflammation signals and how they affect HIF function. The HIF mediated response is regulated both at the transcriptional and post-translational level. I aim to understand this complex system via the establishment of a computer simulation model.

Sueng-Nam received her PhD in Biomedical Sciences in Dr. Joo Hun Ha's Laboratory at Kyung-Hee University in South Korea. There she studied HIF-1a stabilization by Reactive Oxygen Species (ROS) and the regulation of HIF-1a by AMPK.

I am currently studying the role of Nitric Oxide (NO) in the skin.

Na Zhang received her Master Degree from Zhejiang University
(Hangzhou, China) in 2005. Her previous research in Dr. Jian-Guo Geng’s lab in the Shanghai Institutes for Biological Research was focused on Slit/Robo signaling in tumor angiogenesis.

In April 2006, Na Zhang joined Randy Johnson’s lab.
My current research project is to investigate the physiological role
of FIH (factor inhibiting HIF1alpha) by generating FIH knockout
mice.

Courtney graduated from UCSD with a B.S. in Human Biology.

I am currently studying the effect of potential HIF inducers on HIF target gene expression.