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Jeff Hasty

Jeff Hasty

Professor
Section of Molecular Biology/Bioengineering, UCSD

e-mail: jmhasty@ucsd.edu
Lab Homepage: Hasty Lab

Dr. Hasty's research focuses on the construction and utilization of synthetic
gene circuits for dissecting, analyzing, and controlling the dynamical interactions involved in gene regulation.


Tal Danino, Octavio Mondragón-Palomino, Lev Tsimring, Jeff Hasty (2010).  A synchronized quorum of genetic clocks.  Nature 426:326-330.

Natalie Cookson, Scott Cookson, Lev Tsimring, Jeff Hasty (2009). 
Cell cycle-dependent variations in protein concentration.  Nucleic Acids Research 1-6.

Natalie Cookson, Lev Tsimring, Jeff Hasty (2009). 
The pedestrian watchmaker: Genetic clocks from engineered oscillators.  FEBS Letters 583:3931–3937.

Matthew Bennett, Jeff Hasty (2009). 
Microfluidic devices for measuring gene network dynamics in single cells.  Nature Reviews Genetics, 10:628-638.

Jesse Stricker, Scott Cookson, Matthew Bennett, William Mather, Lev Tsimring, Jeff Hasty (2008). 
A fast, robust and tunable synthetic gene oscillator.  Nature 456:516-519.

Matthew Bennett, Wyming Lee Pang, Natalie Ostroff, Bridget Baumgartner, Sujata Nayak, Lev Tsimring, Jeff Hasty (2008). 
Metabolic gene regulation in a dynamically changing environment.  Nature 454:1119-1122.


Jeff Hasty received his Ph.D. in Physics from the Georgia Institute of Technology in 1997, where he worked with Kurt Wiesenfeld. He was a postdoctoral fellow with Jorge Vinals at the Supercomputing Research Institute ('97-'98), and a postdoctoral fellow with Jim Collins in the Applied BioDynamics Lab at Boston University ('98-'01). Somewhere during his postdoctoral stay at Boston University, he mutated into a hybrid computational/molecular biologist. He is currently at the University of California, San Diego, where he is a Professor in the Departments of Molecular Biology and Bioengineering, and the Director of the BioCircuits Institute. His main interest is the design and construction of synthetic gene-regulatory and signaling networks.