Jeff Hasty

Professor
Section of Molecular Biology/Bioengineering, UCSD

e-mail: jmhasty@ucsd.edu

Dr. Hasty's research focuses on the construction and utilization of synthetic
gene circuits for dissecting, analyzing, and controlling the dynamical interactions involved in gene regulation.

Tal Danino, Octavio Mondragón-Palomino, Lev Tsimring, Jeff Hasty (2010).  A synchronized quorum of genetic clocks.  Nature 426:326-330.

Natalie Cookson, Scott Cookson, Lev Tsimring, Jeff Hasty (2009).  Cell cycle-dependent variations in protein concentration.  Nucleic Acids Research 1-6.

Natalie Cookson, Lev Tsimring, Jeff Hasty (2009).  The pedestrian watchmaker: Genetic clocks from engineered oscillators.  FEBS Letters 583:3931–3937.

Matthew Bennett, Jeff Hasty (2009).  Microfluidic devices for measuring gene network dynamics in single cells.  Nature Reviews Genetics, 10:628-638.

Jesse Stricker, Scott Cookson, Matthew Bennett, William Mather, Lev Tsimring, Jeff Hasty (2008).  A fast, robust and tunable synthetic gene oscillator.  Nature 456:516-519.

Matthew Bennett, Wyoming Lee Pang, Natalie Ostroff, Bridget Baumgartner, Sujata Nayak, Lev Tsimring, Jeff Hasty (2008).  Metabolic gene regulation in a dynamically changing environment.  Nature 454:1119-1122.

Jeff Hasty received his Ph.D. in Physics from the Georgia Institute of Technology in 1997, where he worked with Kurt Wiesenfeld. He was a postdoctoral fellow with Jorge Vinals at the Supercomputing Research Institute ('97-'98), and a postdoctoral fellow with Jim Collins in the Applied BioDynamics Lab at Boston University ('98-'01). Somewhere during his postdoctoral stay at Boston University, he mutated into a hybrid computational/molecular biologist. He is currently at the University of California, San Diego, where he is a Professor in the Departments of Molecular Biology and Bioengineering, and the Director of the BioCircuits Institute. His main interest is the design and construction of synthetic gene-regulatory and signaling networks.