Localization of the Akt/PKB PH
domain to the leading edge of chemotaxing cells: Small version
Time-lapse video microscopy of the PH
domain from the serine/threonine kinase Akt/PKB fused to GFP in cells chemotaxing
to cAMP. The position of the micropipette is in the upper left corner of
the frame (not visible). Note localization of the PH domain to the leading
edge of many of the cells. R. Meili and C. Ellsworth, Firtel lab.